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Condition optimization of eco-friendly RP-HPLC and MCR methods via Box–Behnken design and six sigma approach for detecting antibiotic residues

A precise, Eco-friendly, and highly sensitive RP-HPLC method was employed using quality-by-design principles to concurrently identify cephalexin and cefixime residues in the manufacturing machines using a hypersil BDS C18 column (250 × 4.6 mm, 5 μm) at wavelength 254 nm. The Box–Behnken design was a...

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Detalles Bibliográficos
Autores principales: Y. A. Alanazi, Tahani, Adel Pashameah, Rami, Y. Binsaleh, Ammena, A. Mohamed, Mahmoud, A. Ahmed, Hoda, F. Nassar, Hossam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514345/
https://www.ncbi.nlm.nih.gov/pubmed/37735531
http://dx.doi.org/10.1038/s41598-023-40010-1