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Drug repurposing based on the similarity gene expression signatures to explore for potential indications of quercetin: a case study of multiple sclerosis

Quercetin (QR) is a natural flavonol compound widely distributed in the plant kingdom with extensive pharmacological effects. To find the potential clinical indications of QR, 156 differentially expressed genes (DEGs) regulated by QR were obtained from the Gene Expression Omnibus database, and new p...

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Detalles Bibliográficos
Autores principales: Chen, Yulong, Zhang, Mingliang, Li, Weixia, Wang, Xiaoyan, Chen, Xiaofei, Wu, Yali, Zhang, Hui, Yang, Liuqing, Han, Bing, Tang, Jinfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514366/
https://www.ncbi.nlm.nih.gov/pubmed/37744058
http://dx.doi.org/10.3389/fchem.2023.1250043