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The kynurenine pathway in HIV, frailty and inflammaging

Kynurenine (Kyn) is a circulating tryptophan (Trp) catabolite generated by enzymes including IDO1 that are induced by inflammatory cytokines such as interferon-gamma. Kyn levels in circulation increase with age and Kyn is implicated in several age-related disorders including neurodegeneration, osteo...

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Detalles Bibliográficos
Autores principales: Sultana, Shabiha, Elengickal, Anthony, Bensreti, Husam, de Chantemèle, Eric Belin, McGee-Lawrence, Meghan E., Hamrick, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514395/
https://www.ncbi.nlm.nih.gov/pubmed/37744363
http://dx.doi.org/10.3389/fimmu.2023.1244622