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IL-17a-producing γδT cells and NKG2D signaling mediate bacterial endotoxin-induced neonatal lung injury: implications for bronchopulmonary dysplasia

Bronchopulmonary dysplasia (BPD) is a chronic lung disease in preterm birth survivors characterized by inflammation, impaired alveolarization and dysmorphic vasculature. Activated IL-17A+ lymphocytes are key drivers of inflammation in preterm infants. We have shown that in immature mice chronic airw...

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Detalles Bibliográficos
Autores principales: Cui, Tracy X., Brady, Alexander E., Zhang, Ying-Jian, Anderson, Chase, Popova, Antonia P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514485/
https://www.ncbi.nlm.nih.gov/pubmed/37744375
http://dx.doi.org/10.3389/fimmu.2023.1156842