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Polymorphonuclear myeloid-derived suppressor cells and phosphatidylinositol-3 kinase gamma are critical to tobacco-mimicking oral carcinogenesis in mice

BACKGROUND: Oral squamous cell carcinoma (OSCC) is a devastating disease most often associated with tobacco consumption that induces a field of mutations from which a tumor arises. Identification of ways to prevent the emergence of cancer in high-risk patients is an ultimate goal for combatting all...

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Detalles Bibliográficos
Autores principales: Nguyen, Khoa A, DePledge, Lisa N, Bian, Li, Ke, Yao, Samedi, Von, Berning, Amber A, Owens, Philip, Wang, Xiao-Jing, Young, Christian D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514604/
https://www.ncbi.nlm.nih.gov/pubmed/37734878
http://dx.doi.org/10.1136/jitc-2023-007110