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Polymorphonuclear myeloid-derived suppressor cells and phosphatidylinositol-3 kinase gamma are critical to tobacco-mimicking oral carcinogenesis in mice
BACKGROUND: Oral squamous cell carcinoma (OSCC) is a devastating disease most often associated with tobacco consumption that induces a field of mutations from which a tumor arises. Identification of ways to prevent the emergence of cancer in high-risk patients is an ultimate goal for combatting all...
Autores principales: | Nguyen, Khoa A, DePledge, Lisa N, Bian, Li, Ke, Yao, Samedi, Von, Berning, Amber A, Owens, Philip, Wang, Xiao-Jing, Young, Christian D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514604/ https://www.ncbi.nlm.nih.gov/pubmed/37734878 http://dx.doi.org/10.1136/jitc-2023-007110 |
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