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Using CRISPR knock-in of fluorescent tags to examine isoform-specific expression of EGL-19 in C. elegans

L-type voltage-gated calcium channels (VGCCs) regulate calcium influx and excitation-contraction coupling in many types of muscle cells. Thus, VGCC mutations can cause skeletal and cardiac muscle diseases in humans, such as Duchenne muscular dystrophy and Timothy syndrome. To better understand the g...

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Detalles Bibliográficos
Autores principales: McDonald, Kara, Larkin, Kerry, Dickinson, Daniel J, Golden, Andy, Bai, Xiaofei, Doonan, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514701/
https://www.ncbi.nlm.nih.gov/pubmed/37746064
http://dx.doi.org/10.17912/micropub.biology.000858