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Key Features in the Design and Function of Nanocarriers for Intranasal Administration of Gene Therapy in Huntington Disease

A major obstacle to fulfilling the therapeutic promise of gene therapies for hereditary brain diseases, such as Huntington’ Disease (HD), is the requirement for viral vectors and/or an invasive delivery system (stereotaxic injection into brain or infusion into the intrathecal space). HD is an autoso...

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Detalles Bibliográficos
Autores principales: Fihurka, Oksana, Aradi, Stephen, Sava, Vasyl, Sanchez-Ramos, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514752/
https://www.ncbi.nlm.nih.gov/pubmed/37744989
http://dx.doi.org/10.33696/nanotechnol.4.043