Improving 2-Chlorotrityl Chloride (2-CTC) Resin Activation

Used in solid-phase peptide synthesis (SPPS) for peptides with an acid termination, the 2-chlorotrityl chloride (2-CTC) resin is highly susceptible to moisture, leading to reduced resin loading and lower synthetic yields. It is therefore recommended that the resin be activated with thionyl chloride...

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Detalles Bibliográficos
Autores principales: Román, Tanya, Acosta, Gerardo, de la Torre, Beatriz G., Cárdenas, Constanza, Guzmán, Fanny, Albericio, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514796/
https://www.ncbi.nlm.nih.gov/pubmed/37736965
http://dx.doi.org/10.3390/mps6050082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514796/
https://www.ncbi.nlm.nih.gov/pubmed/37736965
http://dx.doi.org/10.3390/mps6050082

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