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Engineering exosomes derived from subcutaneous fat MSCs specially promote cartilage repair as miR-199a-3p delivery vehicles in Osteoarthritis

Osteoarthritis (OA) is a degenerative joint disease involving cartilage. Exosomes derived from Mesenchymal stem cells (MSCs) therapy improves articular cartilage repair, but subcutaneous fat (SC) stromal cells derived exosomes (MSCs(SC)-Exos), especially engineering MSCs(SC)-Exos for drug delivery h...

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Detalles Bibliográficos
Autores principales: Zhao, Shu, Xiu, Guanghui, Wang, Jian, Wen, Yi, Lu, Jinyuan, Wu, Baitong, Wang, Guangming, Yang, Danjing, Ling, Bin, Du, Dajiang, Xu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515007/
https://www.ncbi.nlm.nih.gov/pubmed/37736726
http://dx.doi.org/10.1186/s12951-023-02086-9