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Acute myeloid leukemia-derived exosomes deliver miR-24-3p to hinder the T-cell immune response through DENN/MADD targeting in the NF-κB signaling pathways

BACKGROUND: microRNAs (miRNAs) are known as potent gene expression regulators, and several studies have revealed the prognostic value of miRNAs in acute myeloid leukemia (AML) patient survival. Recently, strong evidence has indicated that miRNAs can be transported by exosomes (EXOs) from cancer cell...

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Detalles Bibliográficos
Autores principales: Otmani, Khalid, Rouas, Redouane, Lagneaux, Laurence, Krayem, Mohammad, Duvillier, Hugues, Berehab, Mimoune, Lewalle, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515055/
https://www.ncbi.nlm.nih.gov/pubmed/37735672
http://dx.doi.org/10.1186/s12964-023-01259-1