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Integrating single-nucleus sequence profiling to reveal the transcriptional dynamics of Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis

BACKGROUND: Alzheimer's disease (AD), Parkinson's disease (PD), and multiple sclerosis (MS) are three nervous system diseases that partially overlap clinically and genetically. However, bulk RNA-sequencing did not accurately detect the core pathogenic molecules in them. The availability of...

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Detalles Bibliográficos
Autores principales: Fan, Li-Yuan, Yang, Jing, Liu, Ruo-Yu, Kong, Ying, Guo, Guang-Yu, Xu, Yu-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515258/
https://www.ncbi.nlm.nih.gov/pubmed/37735671
http://dx.doi.org/10.1186/s12967-023-04516-6