Role of Fyn and the interleukin-6-STAT-3-autophagy axis in sarcopenia

Sarcopenia is the progressive loss of muscle mass wherein Fyn regulates STAT3 to decrease autophagy. To elucidate the role of inflammation in Fyn-STAT3-dependent autophagy and sarcopenia, here we aimed to investigate the underlying mechanisms using two mouse models of primary and secondary sarcopeni...

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Detalles Bibliográficos
Autores principales: Sasaki, Tsuyoshi, Yamada, Eijiro, Uehara, Ryota, Okada, Shuichi, Chikuda, Hirotaka, Yamada, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515305/
https://www.ncbi.nlm.nih.gov/pubmed/37744036
http://dx.doi.org/10.1016/j.isci.2023.107717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515305/
https://www.ncbi.nlm.nih.gov/pubmed/37744036
http://dx.doi.org/10.1016/j.isci.2023.107717

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