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Role of Fyn and the interleukin-6-STAT-3-autophagy axis in sarcopenia
Sarcopenia is the progressive loss of muscle mass wherein Fyn regulates STAT3 to decrease autophagy. To elucidate the role of inflammation in Fyn-STAT3-dependent autophagy and sarcopenia, here we aimed to investigate the underlying mechanisms using two mouse models of primary and secondary sarcopeni...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515305/ https://www.ncbi.nlm.nih.gov/pubmed/37744036 http://dx.doi.org/10.1016/j.isci.2023.107717 |