Interplay of TP53 allelic state, blast count, and complex karyotype on survival of patients with AML and MDS

Several clinical and genetic factors impact overall survival (OS) in myelodysplastic neoplasms (MDS) and acute myeloid leukemia (AML), including complex karyotype (CK), TP53 allelic state, and blast count. We analyzed the interplay of these factors by performing Cox regression analysis and by determ...

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Detalles Bibliográficos
Autores principales: Stengel, Anna, Meggendorfer, Manja, Walter, Wencke, Baer, Constance, Nadarajah, Niroshan, Hutter, Stephan, Kern, Wolfgang, Haferlach, Torsten, Haferlach, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Myeloid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515307/
https://www.ncbi.nlm.nih.gov/pubmed/37505914
http://dx.doi.org/10.1182/bloodadvances.2023010312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515307/
https://www.ncbi.nlm.nih.gov/pubmed/37505914
http://dx.doi.org/10.1182/bloodadvances.2023010312

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