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Plasmodium falciparum infection of human erythroblasts induces transcriptional changes associated with dyserythropoiesis

During development down the erythroid lineage, hematopoietic stem cells undergo dramatic changes to cellular morphology and function in response to a complex and tightly regulated program of gene expression. In malaria infection, Plasmodium spp parasites accumulate in the bone marrow parenchyma, and...

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Detalles Bibliográficos
Autores principales: Feldman, Tamar P., Ryan, Yana, Egan, Elizabeth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515311/
https://www.ncbi.nlm.nih.gov/pubmed/37493969
http://dx.doi.org/10.1182/bloodadvances.2023010844