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Electrostatics-Based Computational Design and Experimental Analysis of Buforin II Antimicrobial Peptide Variants with Increased DNA Affinities

[Image: see text] Antimicrobial peptides (AMPs) are promising alternatives to traditional antibiotics in the treatment of bacterial infections in part due to their targeting of generic bacterial structures that make it more difficult to develop drug resistance. In this study, we introduce and implem...

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Detalles Bibliográficos
Autores principales: Li, Qiao, Kim, Gabriela, Jing, Lisha, Ji, Xiaoxuan, Elmore, Donald E., Radhakrishnan, Mala L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515408/
https://www.ncbi.nlm.nih.gov/pubmed/37744799
http://dx.doi.org/10.1021/acsomega.3c04023