BBB opening by low pulsed electric fields, depicted by delayed-contrast MRI, enables efficient delivery of therapeutic doxorubicin doses into mice brains

BACKGROUND: Pharmacological treatment of CNS diseases is limited due to the presence of the blood-brain barrier (BBB). Recent years showed significant advancement in the field of CNS drug delivery enablers, with technologies such as MR-guided focused ultrasound reaching clinical trials. This have in...

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Detalles Bibliográficos
Autores principales: Cooper, Itzik, Last, David, Ravid, Orly, Rand, Daniel, Matsree, Erez, Omesi, Liora, Shemesh, Chen, Liberman, Meir, Zach, Leor, Furman, Orit, Daniels, Dianne, Liraz-Zaltsman, Sigal, Mardor, Yael, Sharabi, Shirley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515428/
https://www.ncbi.nlm.nih.gov/pubmed/37737197
http://dx.doi.org/10.1186/s12987-023-00468-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515428/
https://www.ncbi.nlm.nih.gov/pubmed/37737197
http://dx.doi.org/10.1186/s12987-023-00468-7

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