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Hypoxia-induced AFAP1L1 regulates pathological neovascularization via the YAP-DLL4-NOTCH axis

BACKGROUND: Pathological neovascularization plays a pivotal role in the onset and progression of tumors and neovascular eye diseases. Despite notable advancements in the development of anti-angiogenic medications that target vascular endothelial growth factor (VEGF) and its receptors (VEGFRs), the o...

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Detalles Bibliográficos
Autores principales: Ren, Jun-Song, Bai, Wen, Ding, Jing-Juan, Ge, Hui-Min, Wang, Su-Yu, Chen, Xi, Jiang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515434/
https://www.ncbi.nlm.nih.gov/pubmed/37737201
http://dx.doi.org/10.1186/s12967-023-04503-x