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Engineering Protein Nanoparticles Functionalized with an Immunodominant Coxiella burnetii Antigen to Generate a Q Fever Vaccine

[Image: see text] Coxiella burnetii is the causative agent of Q fever, for which there is yet to be an FDA-approved vaccine. This bacterial pathogen has both extra- and intracellular stages in its life cycle, and therefore both a cell-mediated (i.e., T lymphocyte) and humoral (i.e., antibody) immune...

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Detalles Bibliográficos
Autores principales: Ramirez, Aaron, Felgner, Jiin, Jain, Aarti, Jan, Sharon, Albin, Tyler J., Badten, Alexander J., Gregory, Anthony E., Nakajima, Rie, Jasinskas, Algimantas, Felgner, Philip L., Burkhardt, Amanda M., Davies, D. Huw, Wang, Szu-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515490/
https://www.ncbi.nlm.nih.gov/pubmed/37682243
http://dx.doi.org/10.1021/acs.bioconjchem.3c00317