Intrinsically Disordered Flanking Regions Increase the Affinity of a Transcriptional Coactivator Interaction across Vertebrates

[Image: see text] Interactions between two proteins are often mediated by a disordered region in one protein binding to a groove in a folded interaction domain in the other one. While the main determinants of a certain interaction are typically found within a well-defined binding interface involving...

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Detalles Bibliográficos
Autores principales: Karlsson, Elin, Ottoson, Carl, Ye, Weihua, Andersson, Eva, Jemth, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515491/
https://www.ncbi.nlm.nih.gov/pubmed/37647499
http://dx.doi.org/10.1021/acs.biochem.3c00285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515491/
https://www.ncbi.nlm.nih.gov/pubmed/37647499
http://dx.doi.org/10.1021/acs.biochem.3c00285

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