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Analysis of a mouse germ cell tumor model establishes pluripotency-associated miRNAs as conserved serum biomarkers for germ cell cancer detection

Malignant testicular germ cells tumors (TGCTs) are the most common solid cancers in young men. Current TGCT diagnostics include conventional serum protein markers, but these lack the sensitivity and specificity to serve as accurate markers across all TGCT subtypes. MicroRNAs (miRNAs) are small non-c...

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Detalles Bibliográficos
Autores principales: Loehr, Amanda R., Timmerman, Dennis M., Liu, Michelle, Gillis, Ad J.M., Matthews, Melia, Bloom, Jordana C., Nicholls, Peter K., Page, David C., Miller, Andrew D., Looijenga, Leendert H.J., Weiss, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515752/
https://www.ncbi.nlm.nih.gov/pubmed/37745561
http://dx.doi.org/10.1101/2023.09.09.556995