Multi-OMIC analysis of Huntington disease reveals a neuroprotective astrocyte state

Huntington disease (HD) is an incurable neurodegenerative disease characterized by neuronal loss and astrogliosis. One hallmark of HD is the selective neuronal vulnerability of striatal medium spiny neurons. To date, the underlying mechanisms of this selective vulnerability have not been fully defin...

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Detalles Bibliográficos
Autores principales: Paryani, Fahad, Kwon, Ji-Sun, Ng, Chris W, Madden, Nacoya, Ofori, Kenneth, Tang, Alice, Lu, Hong, Li, Juncheng, Mahajan, Aayushi, Davidson, Shawn M., Basile, Anna, McHugh, Caitlin, Vonsattel, Jean Paul, Hickman, Richard, Zody, Michael, Houseman, David E., Goldman, James E., Yoo, Andrew S., Menon, Vilas, Al-Dalahmah, Osama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515780/
https://www.ncbi.nlm.nih.gov/pubmed/37745577
http://dx.doi.org/10.1101/2023.09.08.556867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515780/
https://www.ncbi.nlm.nih.gov/pubmed/37745577
http://dx.doi.org/10.1101/2023.09.08.556867

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