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Examining DNA Breathing with pyDNA-EPBD

MOTIVATION: The two strands of the DNA double helix locally and spontaneously separate and recombine in living cells due to the inherent thermal DNA motion.This dynamics results in transient openings in the double helix and is referred to as “DNA breathing” or “DNA bubbles.” The propensity to form l...

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Detalles Bibliográficos
Autores principales: Kabir, Anowarul, Bhattarai, Manish, Rasmussen, Kim Ø., Shehu, Amarda, Usheva, Anny, Bishop, Alan R, Alexandrov, Boian S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515784/
https://www.ncbi.nlm.nih.gov/pubmed/37745370
http://dx.doi.org/10.1101/2023.09.09.557010