Engineering synthetic phosphorylation signaling networks in human cells

Protein phosphorylation signaling networks play a central role in how cells sense and respond to their environment. Here, we describe the engineering of artificial phosphorylation networks in which “push-pull” motifs—reversible enzymatic phosphorylation cycles consisting of opposing kinase and phosp...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoyu, Rocks, Jason W., Jiang, Kaiyi, Walters, Andrew J., Rai, Kshitij, Liu, Jing, Nguyen, Jason, Olson, Scott D., Mehta, Pankaj, Collins, James J., Daringer, Nichole M, Bashor, Caleb J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515791/
https://www.ncbi.nlm.nih.gov/pubmed/37745327
http://dx.doi.org/10.1101/2023.09.11.557100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515791/
https://www.ncbi.nlm.nih.gov/pubmed/37745327
http://dx.doi.org/10.1101/2023.09.11.557100

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