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Engineering synthetic phosphorylation signaling networks in human cells
Protein phosphorylation signaling networks play a central role in how cells sense and respond to their environment. Here, we describe the engineering of artificial phosphorylation networks in which “push-pull” motifs—reversible enzymatic phosphorylation cycles consisting of opposing kinase and phosp...
Autores principales: | Yang, Xiaoyu, Rocks, Jason W., Jiang, Kaiyi, Walters, Andrew J., Rai, Kshitij, Liu, Jing, Nguyen, Jason, Olson, Scott D., Mehta, Pankaj, Collins, James J., Daringer, Nichole M, Bashor, Caleb J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515791/ https://www.ncbi.nlm.nih.gov/pubmed/37745327 http://dx.doi.org/10.1101/2023.09.11.557100 |
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