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Identifying latent genetic interactions in genome-wide association studies using multiple traits

Genome-wide association studies of complex traits frequently find that SNP-based estimates of heritability are considerably smaller than estimates from classic family-based studies. This ‘missing’ heritability may be partly explained by genetic variants interacting with other genes or environments t...

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Detalles Bibliográficos
Autores principales: Bass, Andrew J., Bian, Shijia, Wingo, Aliza P., Wingo, Thomas S., Cutler, David J., Epstein, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515795/
https://www.ncbi.nlm.nih.gov/pubmed/37745553
http://dx.doi.org/10.1101/2023.09.11.557155