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Global brain activity and its coupling with cerebrospinal fluid flow is related to tau pathology

Amyloid-β (Aβ) and tau deposition constitute Alzheimer’s disease (AD) neuropathology. Cortical tau deposits first in the entorhinal cortex and hippocampus and then propagates to neocortex in an Aβ-dependent manner. Tau also tends to accumulate earlier in higher-order association cortex than in lower...

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Detalles Bibliográficos
Autores principales: Han, Feng, Lee, JiaQie, Chen, Xi, Ziontz, Jacob, Ward, Tyler, Landau, Susan M, Baker, Suzanne L, Harrison, Theresa M, Jagust, William J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515801/
https://www.ncbi.nlm.nih.gov/pubmed/37745434
http://dx.doi.org/10.1101/2023.09.12.557492