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Lipid peroxidation drives liquid-liquid phase separation and disrupts raft protein partitioning in biological membranes

The peroxidation of membrane lipids by free radicals contributes to aging, numerous diseases, and ferroptosis, an iron-dependent form of cell death. Peroxidation changes the structure, conformation and physicochemical properties of lipids, leading to major membrane alterations including bilayer thin...

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Detalles Bibliográficos
Autores principales: Balakrishnan, Muthuraj, Kenworthy, Anne K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515805/
https://www.ncbi.nlm.nih.gov/pubmed/37745342
http://dx.doi.org/10.1101/2023.09.12.557355