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Lipid peroxidation drives liquid-liquid phase separation and disrupts raft protein partitioning in biological membranes
The peroxidation of membrane lipids by free radicals contributes to aging, numerous diseases, and ferroptosis, an iron-dependent form of cell death. Peroxidation changes the structure, conformation and physicochemical properties of lipids, leading to major membrane alterations including bilayer thin...
Autores principales: | Balakrishnan, Muthuraj, Kenworthy, Anne K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515805/ https://www.ncbi.nlm.nih.gov/pubmed/37745342 http://dx.doi.org/10.1101/2023.09.12.557355 |
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