Uncoupling the TFIIH Core and Kinase Modules Leads To Unregulated RNA Polymerase II CTD Serine 5 Phosphorylation

TFIIH is an essential transcription initiation factor for RNA polymerase II (RNApII). This multi-subunit complex comprises two modules that are physically linked by the subunit Tfb3 (MAT1 in metazoans). The TFIIH Core Module, with two DNA-dependent ATPases and several additional subunits, promotes D...

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Detalles Bibliográficos
Autores principales: Giordano, Gabriela, Buratowski, Robin, Jeronimo, Célia, Poitras, Christian, Robert, François, Buratowski, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515806/
https://www.ncbi.nlm.nih.gov/pubmed/37745343
http://dx.doi.org/10.1101/2023.09.11.557269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515806/
https://www.ncbi.nlm.nih.gov/pubmed/37745343
http://dx.doi.org/10.1101/2023.09.11.557269

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