Cas13d-mediated isoform-specific RNA knockdown with a unified computational and experimental toolbox

Alternative splicing is an essential mechanism for diversifying proteins, in which mature RNA isoforms produce proteins with potentially distinct functions. Two major challenges in characterizing the cellular function of isoforms are the lack of experimental methods to specifically and efficiently m...

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Detalles Bibliográficos
Autores principales: Schertzer, Megan D., Stirn, Andrew, Isaev, Keren, Pereira, Laura, Das, Anjali, Harbison, Claire, Park, Stella H., Wessels, Hans-Hermann, Sanjana, Neville E., Knowles, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515814/
https://www.ncbi.nlm.nih.gov/pubmed/37745416
http://dx.doi.org/10.1101/2023.09.12.557474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515814/
https://www.ncbi.nlm.nih.gov/pubmed/37745416
http://dx.doi.org/10.1101/2023.09.12.557474

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