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Cas13d-mediated isoform-specific RNA knockdown with a unified computational and experimental toolbox
Alternative splicing is an essential mechanism for diversifying proteins, in which mature RNA isoforms produce proteins with potentially distinct functions. Two major challenges in characterizing the cellular function of isoforms are the lack of experimental methods to specifically and efficiently m...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515814/ https://www.ncbi.nlm.nih.gov/pubmed/37745416 http://dx.doi.org/10.1101/2023.09.12.557474 |