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Magnetically Powered Microwheel Thrombolysis of Occlusive Thrombi in Zebrafish

Tissue plasminogen activator (tPA) is the only FDA approved treatment for ischemic stroke but carries significant risks, including major hemorrhage. Additional options are needed, especially in small vessel thrombi which account for ~25% of ischemic strokes. We have previously shown that tPA-functio...

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Detalles Bibliográficos
Autores principales: Pontius, M. Hao Hao, Ku, Chia-Jui, Osmond, Matthew, Disharoon, Dante, Liu, Yang, Marr, David W.M., Neeves, Keith B., Shavit, Jordan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515822/
https://www.ncbi.nlm.nih.gov/pubmed/37745422
http://dx.doi.org/10.1101/2023.09.11.557256