Clustering of cortical dynein regulates the mechanics of spindle orientation in human mitotic cells

The forces which orient the spindle in human cells remain poorly understood due to a lack of direct mechanical measurements in mammalian systems. We use magnetic tweezers to measure the force on human mitotic spindles. Combining the spindle’s measured resistance to rotation, the speed it rotates aft...

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Detalles Bibliográficos
Autores principales: Anjur-Dietrich, Maya I., Hererra, Vicente Gomez, Farhadifar, Reza, Wu, Haiyin, Merta, Holly, Bahmanyar, Shirin, Shelley, Michael J., Needleman, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515834/
https://www.ncbi.nlm.nih.gov/pubmed/37745442
http://dx.doi.org/10.1101/2023.09.11.557210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515834/
https://www.ncbi.nlm.nih.gov/pubmed/37745442
http://dx.doi.org/10.1101/2023.09.11.557210

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