Comparison of the three-dimensional chromatin structures of adolescent and adult peripheral blood B cells: implications for the study of pediatric autoimmune diseases

BACKGROUND/PURPOSE: Knowledge of the 3D genome is essential to elucidate genetic mechanisms driving autoimmune diseases. The 3D genome is distinct for each cell type, and it is uncertain whether cell lines faithfully recapitulate the 3D architecture of primary human cells or whether developmental as...

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Detalles Bibliográficos
Autores principales: Jiang, Kaiyu, Fu, Yao, Kelly, Jennifer A., Gaffney, Patrick M., Holmes, Lucy C., Jarvis, James N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515843/
https://www.ncbi.nlm.nih.gov/pubmed/37745336
http://dx.doi.org/10.1101/2023.09.11.557171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515843/
https://www.ncbi.nlm.nih.gov/pubmed/37745336
http://dx.doi.org/10.1101/2023.09.11.557171

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