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Plasma membrane abundance dictates phagocytic capacity and functional crosstalk in myeloid cells

Professional phagocytes like neutrophils and macrophages tightly control what they eat, how much they eat, and when they move after eating. We show that plasma membrane abundance is a key arbiter of these cellular behaviors. Neutrophils and macrophages lacking the G-protein subunit Gb4 exhibit profo...

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Detalles Bibliográficos
Autores principales: Winer, Benjamin Y., Settle, Alexander H., Yakimov, Alexandrina M., Jeronimo, Carlos, Lazarov, Tomi, Tipping, Murray, Saoi, Michelle, Sawh, Anjelique, Sepp, Anna-Liisa L., Galiano, Michael, Wong, Yung Yu, Perry, Justin S. A., Geissmann, Frederic, Cross, Justin, Zhou, Ting, Kam, Lance C., Pasoli, Hilda Amalia, Hohl, Tobias, Cyster, Jason G., Weiner, Orion D., Huse, Morgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515848/
https://www.ncbi.nlm.nih.gov/pubmed/37745515
http://dx.doi.org/10.1101/2023.09.12.556572