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Resolving the nanoscale structure of β-sheet assemblies using single-molecule orientation-localization microscopy

Synthetic peptides that self-assemble into cross-β fibrils have remarkable utility as engineered biomaterials due to their modularity and biocompatibility, but their structural and morphological similarity to amyloid species has been a long-standing concern for their translation. Further, their poly...

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Detalles Bibliográficos
Autores principales: Zhou, Weiyan, O’Neill, Conor L., Ding, Tianben, Zhang, Oumeng, Rudra, Jai S., Lew, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515885/
https://www.ncbi.nlm.nih.gov/pubmed/37745382
http://dx.doi.org/10.1101/2023.09.13.557571