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Lysosomal TMEM106B interacts with galactosylceramidase to regulate myelin lipid metabolism

TMEM106B is an endolysosomal transmembrane protein not only associated with multiple neurological disorders including frontotemporal dementia, Alzheimer’s disease, and hypomyelinating leukodystrophy but also potentially involved in COVID-19. Additionally, recent studies have identified amyloid fibri...

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Detalles Bibliográficos
Autores principales: Takahashi, Hideyuki, Perez-Canamas, Azucena, Ye, Hongping, Han, Xianlin, Strittmatter, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515910/
https://www.ncbi.nlm.nih.gov/pubmed/37745346
http://dx.doi.org/10.1101/2023.09.14.557804