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Lysosomal TMEM106B interacts with galactosylceramidase to regulate myelin lipid metabolism
TMEM106B is an endolysosomal transmembrane protein not only associated with multiple neurological disorders including frontotemporal dementia, Alzheimer’s disease, and hypomyelinating leukodystrophy but also potentially involved in COVID-19. Additionally, recent studies have identified amyloid fibri...
Autores principales: | Takahashi, Hideyuki, Perez-Canamas, Azucena, Ye, Hongping, Han, Xianlin, Strittmatter, Stephen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515910/ https://www.ncbi.nlm.nih.gov/pubmed/37745346 http://dx.doi.org/10.1101/2023.09.14.557804 |
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