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Phosphoproteomics reveals content and signaling differences between neonatal and adult platelets

BACKGROUND AND OBJECTIVE: Recent clinical studies have shown that transfusions of adult platelets increase morbidity and mortality in preterm infants. Neonatal platelets are hyporesponsive to agonist stimulation, and emerging evidence suggests developmental differences in platelet immune functions....

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Detalles Bibliográficos
Autores principales: Thom, Christopher S, Davenport, Patricia, Fazelinia, Hossein, Liu, Zhi-Jian, Zhang, Haorui, Ding, Hua, Roof, Jennifer, Spruce, Lynn A, Ischiropoulos, Harry, Sola-Visner, Martha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515911/
https://www.ncbi.nlm.nih.gov/pubmed/37745418
http://dx.doi.org/10.1101/2023.09.13.557268