BET inhibition rescues ciliogenesis and ameliorates pancreatitis-driven phenotypic changes in mice with Par3 loss

The apical-basal polarity of pancreatic acinar cells is essential for maintaining tissue architecture. However, the mechanisms by which polarity proteins regulate acinar pancreas tissue homeostasis are poorly understood. Here, we evaluate the role of Par3 in acinar pancreas injury and homeostasis. W...

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Detalles Bibliográficos
Autores principales: Shields, Mario A., Metropulos, Anastasia E., Spaulding, Christina, Hirose, Tomonori, Ohno, Shigeo, Pham, Thao N.D., Munshi, Hidayatullah G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515915/
https://www.ncbi.nlm.nih.gov/pubmed/37745543
http://dx.doi.org/10.1101/2023.09.14.557654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515915/
https://www.ncbi.nlm.nih.gov/pubmed/37745543
http://dx.doi.org/10.1101/2023.09.14.557654

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