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Determinants of DDX3X sensitivity uncovered using a helicase activity in translation reporter
DDX3X regulates the translation of a subset of human transcripts containing complex 5′ untranslated regions (5′ UTRs). In this study we developed the helicase activity reporter for translation (HART) which uses DDX3X-sensitive 5′ UTRs to measure DDX3X mediated translational activity in cells. To dis...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515938/ https://www.ncbi.nlm.nih.gov/pubmed/37745530 http://dx.doi.org/10.1101/2023.09.14.557805 |