Acod1 Expression in Cancer Cells Promotes Immune Evasion through the Generation of Inhibitory Peptides

Targeting PD-1 is an important component of many immune checkpoint blockade (ICB) therapeutic approaches. However, ICB is not an efficacious strategy in a variety of cancer types, in part due to immunosuppressive metabolites in the tumor microenvironment (TME). Here, we find that αPD-1-resistant can...

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Detalles Bibliográficos
Autores principales: Schofield, James H., Longo, Joseph, Sheldon, Ryan D., Albano, Emma, Hawk, Mark A., Murphy, Sean, Duong, Loan, Rahmy, Sharif, Lu, Xin, Jones, Russell G., Schafer, Zachary T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515953/
https://www.ncbi.nlm.nih.gov/pubmed/37745450
http://dx.doi.org/10.1101/2023.09.14.557799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515953/
https://www.ncbi.nlm.nih.gov/pubmed/37745450
http://dx.doi.org/10.1101/2023.09.14.557799

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