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Acod1 Expression in Cancer Cells Promotes Immune Evasion through the Generation of Inhibitory Peptides
Targeting PD-1 is an important component of many immune checkpoint blockade (ICB) therapeutic approaches. However, ICB is not an efficacious strategy in a variety of cancer types, in part due to immunosuppressive metabolites in the tumor microenvironment (TME). Here, we find that αPD-1-resistant can...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515953/ https://www.ncbi.nlm.nih.gov/pubmed/37745450 http://dx.doi.org/10.1101/2023.09.14.557799 |