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Global impact of aberrant splicing on human gene expression levels

Alternative splicing (AS) is pervasive in human genes, yet the specific function of most AS events remains unknown. It is widely assumed that the primary function of AS is to diversify the proteome, however AS can also influence gene expression levels by producing transcripts rapidly degraded by non...

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Detalles Bibliográficos
Autores principales: Fair, Benjamin, Najar, Carlos Buen Abad, Zhao, Junxing, Lozano, Stephanie, Reilly, Austin, Mossian, Gabriela, Staley, Jonathan P, Wang, Jingxin, Li, Yang I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515962/
https://www.ncbi.nlm.nih.gov/pubmed/37745605
http://dx.doi.org/10.1101/2023.09.13.557588