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Poly-basic peptides and polymers as new drug candidate against Plasmodium falciparum

Plasmodium falciparum, the malaria-causing parasite, is a leading cause of infection-induced deaths worldwide. The preferred treatment approach is artemisinin-combination therapy, which couples fast-acting artemisinin derivatives with longer-acting drugs like lumefantrine, mefloquine, and amodiaquin...

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Detalles Bibliográficos
Autores principales: Sivakumar, Roshan, Floyd, Katherine, Jessey, Erath, Kim, Jenny Kim, Bayguinov, Peter O., Fitzpatrick, James A.J., Goldfrab, Dennis, Jovanovic, Marko, Tripathi, Abhai, Djuranovic, Sergej, Pavlovic-Djuranovic, Slavica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516022/
https://www.ncbi.nlm.nih.gov/pubmed/37745508
http://dx.doi.org/10.1101/2023.09.16.558069