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The Pex6 N1 domain is required for Pex15 binding and proper assembly with Pex1

The heterohexameric AAA-ATPase Pex1/Pex6 is essential for the formation and maintenance of peroxisomes. Pex1/Pex6, similar to other AAA-ATPases, uses the energy from ATP hydrolysis to mechanically thread substrate proteins through its central pore, thereby unfolding them. In related AAA-ATPase motor...

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Detalles Bibliográficos
Autores principales: Ali, Bashir A., Judy, Ryan M., Chowdhury, Saikat, Jacobsen, Nicole K., Castanzo, Dominic T., Carr, Kaili L., Richardson, Chris D., Lander, Gabriel C., Martin, Andreas, Gardner, Brooke M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516024/
https://www.ncbi.nlm.nih.gov/pubmed/37745580
http://dx.doi.org/10.1101/2023.09.15.557798