A robust knock-in approach using a minimal promoter and a minicircle

Knock-in reporter (KI) animals are essential tools in biomedical research to study gene expression impacting diverse biological events. While CRISPR/Cas9-mediated genome editing allows for the successful generation of KI animals, several factors should be considered, such as low expression of the ta...

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Detalles Bibliográficos
Autores principales: Keating, Margaret, Hagle, Ryan, Osorio-Mendez, Daniel, Rodriguez-Parks, Anjelica, Almutawa, Sarah I, Kang, Junsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516040/
https://www.ncbi.nlm.nih.gov/pubmed/37745465
http://dx.doi.org/10.1101/2023.09.15.558008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516040/
https://www.ncbi.nlm.nih.gov/pubmed/37745465
http://dx.doi.org/10.1101/2023.09.15.558008

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