Single-cell nascent RNA sequencing using click-chemistry unveils coordinated transcription

Transcription is the primary regulatory step in gene expression. Divergent transcription initiation from promoters and enhancers produces stable RNAs from genes and unstable RNAs from enhancers(1–5). Nascent RNA capture and sequencing assays simultaneously measure gene and enhancer activity in cell...

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Detalles Bibliográficos
Autores principales: Mahat, Dig B., Tippens, Nathaniel D., Martin-Rufino, Jorge D., Waterton, Sean K., Fu, Jiayu, Blatt, Sarah E., Sharp, Phillip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516050/
https://www.ncbi.nlm.nih.gov/pubmed/37745427
http://dx.doi.org/10.1101/2023.09.15.558015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516050/
https://www.ncbi.nlm.nih.gov/pubmed/37745427
http://dx.doi.org/10.1101/2023.09.15.558015

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